2023-03-31 14:00:00  Author | Wencheng WANG | Latest academic developments

In human body, vitamin K storage in the liver usually contains about 90% menaquinones (vitamin K2) and 10% phylloquinone (vitamin K1). Vitamin K is widely metabolized in the liver and excreted in urine and bile. Researchers found that about 20% of the injection dose of phylloquinone was recovered in urine, while about 40-50% was excreted in feces through bile. Therefore, it is likely that about 60-70% of K1 absorbed from food will eventually be lost from the body through excreta. These results indicate that the body's storage of vitamin K requires to be continuously replenished.